Vitamin B12 allergy and desensitization

Main Article Content

Öner Özdemir

Keywords

Cyanocobalamin, hypersensitivity, anaphylaxis, drug allergy

Abstract

N/A

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References

1. Yegin Katran Z, Bulut I. Fewer injections, less pain: Successful cyanocobalamin desensitization. Allergol Immunopathol. 2025;53(3):201–3. https://doi.org/10.15586/ aei.v53i3.1320
2. Alves-Correia M, Gaspar A, Borrego LM, Mota I, Morais-Almeida M. Desensitization to cyanocobalamin: Rush Protocol. J Investig Allergol Clin Immunol. 2017;27(3):196–7. https://doi. org/10.18176/jiaci.0160
3. Kartal O, Gulec M, Demirel F, Yesillik S, Caliskaner Z, Sener O. Vitamin B12 allergy and successful desensitisation with cya-nocobalamin: A case report. Allergol Immunopathol (Madr). 2012;40(5):324–5. https://doi.org/10.1016/j.aller.2011.10.003
4. Caballero MR, Lukawska J, Lee TH, Dugué P. Allergy to vitamin B12: Two cases of successful desensitization with cyanocobalamin. Allergy. 2007;62(11):1341–2. https://doi. org/10.1111/j.1398-9995.2007.01389.x
5. Turvey SE, Cronin B, Arnold AD, Twarog FJ, Dioun AF. Adverse reactions to vitamin B12 injections due to benzyl alcohol sensitivity: Successful treatment with intranasal cyanocobalamin. Allergy. 2004;59(9):1023–4. https://doi. org/10.1111/j.1398-9995.2004.00507.x
6. Heyworth-Smith D, Hogan PG. Allergy to hydroxycobalamin, with tolerance of cyanocobalamin. Med J Aust. 2002;177(3):162–3. https://doi.org/10.5694/j.1326-5377.2002.tb04709.x
7. Lis K. Desensitization for vitamin B12 hypersensitivity and how to do it. Biomedicines. 2025;13(4):801. https://doi. org/10.3390/biomedicines13040801